David R Greaves Selected Research

Atherosclerosis

10/2019	The Impact of Cannabinoid Receptor 2 Deficiency on Neutrophil Recruitment and Inflammation.
2/2017	Tracking Monocyte Recruitment and Macrophage Accumulation in Atherosclerotic Plaque Progression Using a Novel hCD68GFP/ApoE-/- Reporter Mouse-Brief Report.
3/2015	RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
1/2015	Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists.
12/2014	Fractalkine promotes human monocyte survival via a reduction in oxidative stress.
11/2014	Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
1/2013	CC chemokine receptors and chronic inflammation--therapeutic opportunities and pharmacological challenges.
3/2012	Anti-inflammatory effects of nicotinic acid in human monocytes are mediated by GPR109A dependent mechanisms.
3/2012	Fractalkine: a survivor's guide: chemokines as antiapoptotic mediators.
3/2010	Inflammatory cell recruitment in cardiovascular disease: murine models and potential clinical applications.

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David R Greaves Research Topics

Disease

40	Inflammation (Inflammations) 02/2022 - 11/2002
25	Atherosclerosis 10/2019 - 01/2003
9	Peritonitis 01/2022 - 11/2002
6	Atherosclerotic Plaque (Atheroma) 02/2017 - 11/2003
5	Infections 12/2018 - 01/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 12/2014 - 04/2009
3	Vascular System Injuries 09/2013 - 04/2007
3	Asthma (Bronchial Asthma) 02/2013 - 01/2003
2	Colitis 10/2019 - 07/2011
2	Multiple Sclerosis 10/2019 - 01/2016
2	Metabolic Diseases (Metabolic Disease) 01/2018 - 03/2009
2	Aortic Aneurysm (Aneurysm, Aortic) 02/2017 - 03/2015
2	Vascular Diseases (Vascular Disease) 03/2015 - 03/2012
2	Arthritis (Polyarthritis) 01/2015 - 11/2014
2	Hyperplasia 09/2013 - 04/2007
2	Rheumatoid Arthritis 01/2013 - 01/2003
2	Pathologic Constriction (Stenosis) 04/2007 - 05/2005
2	Neointima 05/2005 - 11/2003
1	Neoplasms (Cancer) 01/2022
1	Proteinuria 10/2020
1	Obesity 10/2020
1	Multiple Organ Failure (MODS) 01/2020
1	Sepsis (Septicemia) 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Heart Injuries 01/2020
1	Cicatrix (Scar) 01/2020
1	Myocardial Infarction 01/2020
1	Reperfusion Injury 10/2019
1	Pneumonia (Pneumonitis) 01/2019
1	Substance-Related Disorders (Drug Abuse) 02/2018
1	Pain (Aches) 02/2018
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2017
1	Arteritis 02/2017
1	Endotoxemia 01/2017
1	Shock 01/2017
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2016
1	Rupture 03/2015
1	Phenylketonurias (Phenylketonuria) 02/2015
1	Starvation 12/2014
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2014
1	Virus Diseases (Viral Diseases) 04/2014
1	Autoimmune Diseases (Autoimmune Disease) 04/2014
1	Ovarian Neoplasms (Ovarian Cancer) 12/2013
1	Vascular Remodeling 09/2013

Drug/Important Bio-Agent (IBA)

12	ChemokinesIBA 03/2015 - 01/2003
9	ZymosanIBA 01/2022 - 04/2008
9	Proteins (Proteins, Gene)FDA Link 01/2016 - 10/2004
6	CytokinesIBA 01/2020 - 11/2002
6	CC ChemokinesIBA 12/2015 - 01/2003
6	ApolipoproteinsIBA 12/2014 - 10/2004
5	Chemokine CX3CL1IBA 12/2014 - 11/2003
5	Scavenger Receptors (Scavenger Receptor)IBA 03/2010 - 07/2003
4	Cannabinoid Receptors (Cannabinoid Receptor)IBA 10/2019 - 01/2015
4	Apolipoproteins E (ApoE)IBA 02/2017 - 10/2004
3	Pharmaceutical PreparationsIBA 02/2022 - 01/2018
3	LigandsIBA 11/2020 - 01/2008
3	InflammasomesIBA 10/2020 - 04/2014
3	sapropterin (tetrahydrobiopterin)FDA Link 12/2018 - 09/2008
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2018 - 12/2008
3	Biological ProductsIBA 02/2017 - 11/2002
3	Galectin 3 (LGALS3)IBA 02/2017 - 03/2008
3	CholesterolIBA 03/2012 - 06/2005
3	Peptides (Polypeptides)IBA 05/2010 - 04/2008
2	Phosphotransferases (Kinase)IBA 01/2022 - 01/2017
2	Agammaglobulinaemia Tyrosine KinaseIBA 10/2020 - 01/2020
2	ibrutinibIBA 10/2020 - 01/2020
2	Angiotensin IIIBA 02/2017 - 03/2015
2	Interleukin-18 (Interleukin 18)IBA 01/2017 - 08/2015
2	Chemokine ReceptorsIBA 03/2015 - 11/2006
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2015 - 09/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2014 - 09/2008
2	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 09/2013 - 09/2008
2	AdipokinesIBA 03/2010 - 03/2009
2	EnzymesIBA 09/2008 - 10/2006
2	oxidized low density lipoproteinIBA 08/2008 - 01/2005
2	LipidsIBA 06/2005 - 07/2003
2	CX3C Chemokine Receptor 1IBA 04/2004 - 11/2003
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 10/2020
1	CollagenIBA 01/2020
1	acalabrutinibIBA 01/2020
1	Staphylococcal Protein A (Protein A)IBA 01/2019
1	Opioid Analgesics (Opioids)IBA 02/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2018
1	Acetaminophen (Paracetamol)FDA LinkGeneric 02/2018
1	superoxide dismutase 2IBA 10/2017
1	Myeloid Cell Leukemia Sequence 1 ProteinIBA 10/2017
1	Green Fluorescent ProteinsIBA 02/2017
1	InterleukinsIBA 01/2017
1	CalciumIBA 01/2016
1	GlucocorticoidsIBA 01/2016
1	Pathogen-Associated Molecular Pattern MoleculesIBA 08/2015
1	sepiapterinIBA 02/2015
1	Insulin (Novolin)FDA Link 11/2014
1	DNA (Deoxyribonucleic Acid)IBA 04/2014
1	Nitric Oxide Synthase (NO Synthase)IBA 09/2013
1	Protein Glutamine gamma Glutamyltransferase 2IBA 02/2013
1	Transcription Factors (Transcription Factor)IBA 02/2013

Therapy/Procedure

5	Therapeutics 10/2019 - 06/2005
2	Intraperitoneal Injections 01/2009 - 10/2006
2	Intravenous Injections 08/2005 - 10/2004